Bioconjugate Chemistry: Functional Targets. The Chemistry of Reactive Groups. Bioconjugate Reagents: Zero-Length Cross-linkers. Homobifunctional Cross-linkers. Heterobifunctional Cross-linkers. Trifunctional Cross-linkers. Cleavable Reagent Systems. Tags and Probes. Bioconjugate Applications: Preparation of Hapten-Carrier Immunogen Conjugates. Antibody Modification and Conjugation. Immunotoxin Conjugation Techniques. Preparation of Liposome Conjugates and Derivatives. Avidin-Biotin Systems. Preparation of Colloidal-Gold-Labeled Proteins. Modification with Synthetic Polymers. Enzyme Modification and Conjugation. Nucleic Acid and Oligonucleotide Modification and Conjugation. Subject Index.
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